What Is Exosome?
A skin-quality care program designed to help the skin appear smoother, dewier, and healthier.
Dull or dry skin, enlarged-looking pores, uneven texture, or certain acne marks are concerns that many people notice even when they use skincare regularly. This is because skin quality depends on more than hydration alone; it is also related to the condition of the skin layers, skin resilience, care after sun and pollution exposure, rest, and each individual’s skin response.
Exosome is one of the skin-quality care programs attracting interest in aesthetic dermatology. Academic literature describes extracellular vesicles—small vesicles involved in communication between cells. However, research in aesthetic skin applications remains limited, and actual use must follow the selected product’s instructions, accompanying documentation, and the applicable legal requirements of each country.
At LOLLANA CLINIC, choosing a skin-care program should not begin with the program name alone. It should begin with an assessment of the individual’s skin condition, concerns, medical history, and goals so that an appropriate plan can be developed without providing more treatment than necessary.
If you are unsure whether Exosome is suitable for your skin condition, you can contact LOLLANA CLINIC for an initial assessment.
What Is Exosome?
Exosomes are extremely small vesicles within the extracellular-vesicle group that cells release to communicate with other cells. They may contain various biomolecules, including proteins, lipids, and certain types of genetic material. Academic literature indicates that exosomes are involved in intercellular signalling; however, their mechanisms, isolation methods, purity, and product standards still require careful consideration.
In aesthetic skin care, Exosome is commonly discussed as a category of products or programs intended to support skin quality—for example, helping the skin appear more hydrated and smoother, making pores look less noticeable, or supplementing skin care after certain procedures. Suitability must be considered according to the product formulation, method of use, and applicable requirements. Not all products labelled as Exosome have the same properties or methods of use.
Image caption: A cross-sectional illustration of human skin showing its three main layers: the epidermis; the dermis, which contains fibroblasts that produce collagen; and the subcutaneous layer.
How Exosome Is Described as Working
Exosomes are commonly described as “mediators of intercellular communication.” These vesicles can carry certain biomolecules to target cells and may influence processes associated with skin repair, skin elasticity, or the skin’s response to certain types of damage. Reviews in aesthetic dermatology have discussed potential applications in areas such as anti-ageing, wound healing, scar remodelling, and hair regeneration. However, clearer clinical evidence and more data on safety and product standards are still required.
Key Benefits of This Treatment
- Focuses on overall skin quality and is suitable for those who do not want to directly alter their facial contours but want their skin to appear healthier.
- May supplement the care of dull or uneven-looking skin, particularly for those concerned about dryness, lack of radiance, or noticeable pores.
- May be incorporated into a plan with other skin programs, such as Skin Boosters, lasers, microneedling, or other skin-rejuvenation procedures, following an assessment.
- Suitable for a personalised skin plan because individual skin responses differ. The formulation, method of use, and number of sessions should be selected according to the skin condition.
- It is not a volumising filler treatment and is therefore more suitable for those who want to focus on improving the appearance of the skin rather than reshaping the face.
- Products and methods of use should be verifiable. Before treatment, the notification or registration number, accompanying documentation, and permitted use should be checked.
Who Is Exosome Suitable For?
Exosome may be suitable for individuals with the following skin concerns:
- Those whose skin still appears dull or tired even after resting or using skincare.
- Those with dry or dehydrated skin, or skin that lacks a dewy appearance.
- Those concerned about enlarged-looking pores or coarse-looking skin texture.
- Those with acne marks, uneven skin texture, or certain shallow atrophic acne scars who want to plan care in combination with other programs.
- Those beginning to notice fine lines associated with dryness or reduced skin elasticity.
- Those who want to improve overall skin quality without making a noticeable change to facial contours.
- Those with multiple skin concerns who want the clinic to assess whether Exosome or another program would be more appropriate.
For individuals with multiple skin concerns, a skin assessment is recommended before selecting a program so that the plan can be tailored to the person’s actual skin condition.
Who May Not Be Suitable for Exosome, and What Precautions Should Be Considered?
Exosome or this category of skin-quality care programs may not be suitable, or may require consultation with a qualified provider before treatment, in the following situations:
- Individuals who are pregnant or breastfeeding.
- Individuals with an underlying medical condition that is not adequately controlled.
- Individuals with a history of drug allergies, allergies to certain substances, or reactions to multiple categories of skincare products.
- Individuals with an infection, rash, open wound, or inflammation in the treatment area.
- Individuals who have recently undergone an intensive procedure or whose skin has not yet recovered adequately.
- Those seeking to fill deep folds or reshape facial contours, for whom filler treatment may be more suitable.
- Those seeking to directly reduce wrinkles caused by muscle movement, for whom Botox may be more suitable.
- Those expecting guaranteed or identical results for everyone.
Another important precaution is to avoid products that claim to be Exosome without clear supporting information. The U.S. FDA states that exosome products intended to treat diseases or medical conditions are subject to regulation, and there are currently no FDA-approved exosome products in the United States for the treatment of diseases or medical conditions as medically claimed.
What Skin Concerns Can Rejuran Help Address?
Exosome may support the care of the following concerns. Results depend on the skin condition, method of use, product formulation, and any combined treatment plan.
- May help the skin appear more hydrated and refreshed.
- Helping improve the appearance of skin smoothness
- Helping pores appear less noticeable in some individuals
- May supplement the care of tired-looking skin associated with insufficient rest or pollution exposure.
- May help the skin appear healthier and more balanced when incorporated into an appropriate skincare plan.
- May supplement the care of certain acne marks or uneven skin texture when combined with an appropriate program.
- May support a naturally healthier-looking overall skin appearance.
Common Treatment Areas
Areas commonly treated with Exosome programs or other skin-quality support programs include:
- The overall face
- Cheeks
- Forehead
- Around the eyes, only when the product and method of use are appropriate for this area.
- Neck
- Backs of the hands
- Areas where the skin appears dry, tired, or uneven.
- The scalp, only with formulations designed for scalp or hair use. Results depend on the individual condition and its duration.
Actual treatment areas should be determined according to the product documentation, authorised method of use, and a physician’s assessment.
Steps Before Receiving Treatment
Before selecting an Exosome program at LOLLANA CLINIC, a structured assessment should generally include the following steps:
- Initial skin assessment
Assess dryness, oiliness, pores, acne marks, uneven texture, sensitivity to irritation, and the specific skin concerns to be addressed. - Review medical and allergy history
This includes drug or product allergies, underlying medical conditions, pregnancy, breastfeeding, and any recent procedures. - Plan the treatment areas and approach
Determine whether Exosome should be used alone or combined with another program, such as a Skin Booster, laser, microneedling, or a more appropriate skin-rejuvenation option. - Verify the product and method of use
Before treatment, the product source, accompanying documentation, notification or registration number, and appropriate method of use should be checked. - Explain limitations and aftercare
This ensures that the patient understands that results vary, identical outcomes cannot be guaranteed for everyone, and ongoing skin care is required after treatment.
How to Care for Your Skin After Exosome
After an Exosome or skin-quality care program, follow the provider’s aftercare instructions. General guidance may include:
- Avoid touching, picking, scratching, or massaging the treated area during the initial recovery period.
- Avoid makeup and potentially irritating skincare products for the first 24 hours, or follow the clinic’s specific instructions.
- Avoid heat exposure, including saunas, steam rooms, strenuous exercise, and strong sunlight, for the first 24–48 hours.
- Apply sunscreen and keep the skin well moisturized.
- Avoid alcohol during the initial recovery period, particularly if you bruise or swell easily.
- Contact the clinic for further assessment if pain, swelling, redness, warmth, rash, or any unusual symptoms do not improve.
How Soon Are Results Visible After Exosome, and How Long Do They Last?
There is no fixed timeline for Exosome results because they depend on several factors, including the baseline skin condition, specific concerns, method of use, selected product, any combined procedures, and aftercare.
Some individuals may initially feel that their skin appears more hydrated or refreshed. However, changes in smoothness, the appearance of pores, or overall skin quality may take time and may require ongoing care. Studies of Exosome in aesthetic skin applications use varied formulations, methods, and study designs, so results should not be presented as fixed or identical for everyone.
Results vary depending on the baseline skin condition, specific concerns, and individual response. An assessment should be completed before receiving treatment.
How many sessions are needed?
The number of sessions depends on the individual’s skin condition, goals, and care plan. For concerns such as tired-looking skin, dryness, or noticeable pores, treatment may begin with a session-by-session assessment, followed by monitoring before a longer-term plan is established.
For a structured skin-quality care plan, a course may be designed according to the skin concerns and any combined procedures. However, the number of sessions should not be fixed without assessing the actual skin condition because Exosome formulations and methods of use differ.
Comparison with Similar Treatments
| Program | Product/procedure category | General primary mechanism | Suitable For | Expected type of result |
|---|---|---|---|---|
| Exosome | Skin Quality / Skin Rejuvenation Support | Supports intercellular communication and skin quality according to the product information | Tired-looking or dry skin, noticeable pores, uneven texture | Skin may appear brighter, smoother, and healthier depending on the formulation and individual response |
| Rejuran / PN | Polynucleotide Skin Repair Support | Supports skin quality and care for tired-looking skin | Thin or tired-looking skin, noticeable pores, fine lines | Skin may appear healthier and smoother |
| Juvelook | Skin Quality / Collagen Support in selected applications | Supports skin quality and certain forms of uneven texture | Shallow acne scars, uneven texture, noticeable pores | Skin may appear smoother when the plan is appropriate |
| Filler Injection | Dermal Filler | Restores volume or fills deeper fold | Nasolabial folds, under-eye area, chin, temples, or selected areas requiring volume | The face may appear fuller or more defined in the treated areas |
| Botox Injection | Neuromodulator | Reduces activity in selected muscles | Dynamic wrinkles, jaw muscles, or excessive sweating in selected areas | Expression lines may appear softer, or selected muscles may appear more relaxed |
Summary: No single program is suitable for everyone. A Skin Booster may be considered when hydration is the primary goal, while filler may be more suitable for deeper folds. For overall skin-quality care, Exosome may be one of the options assessed alongside other programs.
Exosome Price
Prices start from THB 7,900 for 5 cc.
The price depends on the product formulation, quantity, treatment area, method of use, combined programs, and the care plan tailored to each individual. A skin assessment is recommended before treatment to select an appropriate approach without providing more treatment than necessary.
FAQ: Frequently Asked Questions
Does Exosome hurt?
The sensation during treatment depends on the method of use and any combined procedure. When Exosome is used with a procedure that disrupts the skin barrier, some individuals may experience tightness, tingling, or mild irritation. Ask about the actual procedure before treatment.
How long does swelling last after Exosome?
Mild redness or swelling is often associated with a combined procedure, such as laser treatment, microneedling, or another intervention. The duration depends on the skin condition and individual response. Contact the clinic if swelling or pain is severe or appears unusual.
Can I wear makeup after treatment?
This depends on the treatment method. When Exosome is combined with a procedure that irritates or disrupts the skin barrier, makeup should be avoided during the initial period according to the provider’s instructions to support skin recovery.
Can Exosome be combined with laser treatment?
In some treatment approaches, Exosome may be planned together with lasers or other skin programs. However, the skin should be assessed first because sensitivity to irritation varies between individuals.
How is Exosome different from filler?
Exosome focuses on supporting overall skin quality, while filler is used to restore volume or balance selected areas of the face. The two programs have different purposes and should be selected according to the concern being addressed.
How is Exosome different from a Skin Booster?
HA-based Skin Boosters generally focus on hydration and a plumper, more hydrated appearance. Exosome is more commonly discussed in relation to supporting skin quality and intercellular communication; however, results depend on the product formulation and actual method of use.
What age is Exosome suitable for?
There is no fixed age requirement. Suitability should be based more on the skin condition, specific concerns, and treatment goals than on age alone—for example, tired-looking or dry skin, noticeable pores, or uneven texture.
How frequently is treatment needed?
Frequency depends on the skin condition and care plan. For ongoing skin care, treatment may be planned as a course or performed at intervals assessed by the provider. It should not be performed more frequently than necessary.
Does Exosome have side effects?
Some individuals may experience redness, irritation, skin tightness, or tenderness, particularly when Exosome is combined with another procedure. Clinical reviews also note that further research is needed on safety, product standards, and human-use data. Products and service providers should therefore be verifiable.
Can Exosome help with acne scars?
It may supplement the care of uneven texture or acne marks in some individuals, but it should not be described as a direct treatment for atrophic acne scars. Acne scars vary in type and often require a combined plan, such as laser treatment, microneedling, subcision, or another skin-quality treatment, based on an assessment.
Are Exosome results permanent?
Permanent results should not be expected because skin quality changes with age, sun exposure, pollution, sleep, stress, and ongoing skincare. Results therefore vary between individuals.
For more targeted skin care, contact LOLLANA CLINIC for a skin assessment, a comparison of programs suited to your concerns, and an appropriate care plan—without needing to choose based on the program name alone.
Results vary depending on the baseline skin condition, specific concerns, and individual response. An assessment should be completed before receiving treatment.
References
| Source | Source Type | Information supported |
|---|---|---|
| Exosomes: A Comprehensive Review for the Practicing Dermatologist, Journal of Clinical and Aesthetic Dermatology | Clinical Review Article | Definition of exosomes, their role in intercellular communication, and limitations of the research and safety evidence |
| Exosomes in Skin Rejuvenation: Systematic Review of Anti-Aging Effects and Clinical Applications, Dermatology Practical & Conceptual | Systematic Review | Evidence regarding skin rejuvenation, hydration, elasticity, wrinkles, pigmentation, and research limitations |
| Consumer Alert on Regenerative Medicine Products Including Stem Cells and Exosomes, U.S. FDA | Regulatory / Consumer Alert | Precautions concerning exosome products, regulation, and risks from exaggerated claims |
| Thai FDA clarification on Exosome and Stem Cell technology | Thai FDA / Regulatory Source | Advertising precautions for medical devices claiming Exosome or Stem Cell technology for facial injection |
| Cosmetic notification assessment criteria, Cosmetics and Hazardous Substances Control Division, Thai FDA | Thai FDA Cosmetic Criteria | Terms that may present regulatory risk in cosmetic names or advertising, including Exosome, Stem Cell, Growth Factor, and wording implying injection |
| ASCEplus Official Brand Page | Official Brand / Manufacturer-related Source | Example source for product images or brand information if the clinic actually uses this product |